This website uses cookies. By continuing you are agreeing to our privacy policy.

Xiaoyi Yuan, Ph.D.

University of Texas Health Science Center at Houston
Evaluating Role of MicroRNA as Therapeutic Target for ARDS
Catalyst Award

Approximately 200,000 patients develop acute respiratory distress syndrome (ARDS) annually in the United States, leading to 75,000 deaths. In ARDS, fluid leaks into the lungs, making breathing difficult or impossible. There are no effective treatment or prevention strategies for this deadly disease. We have found that a group of small gene pieces called microRNAs are crucial molecules in changing the levels of inflammation in lung injury. We will study the role of a microRNA called miR-147 in lung inflammation in ARDS. We will evaluate whether these small genes can be targeted for ARDS treatment safely and efficiently in preclinical studies. Our study will lay the groundwork for novel therapeutic approaches for treating patients with ARDS.

Red button with telephone
Ask An Expert

Questions about your lung health? Need help finding healthcare? Call 1-800-LUNGUSA.

Get help
Red button of two hand prints
We need your generous support

Make a difference by delivering research, education and advocacy to those impacted by lung disease.

Button of turquoise LUNG FORCE swirl

LUNG FORCE unites women and their loved ones across the country to stand together in the fight against lung cancer.

Get involved
Join the fight for healthy lungs and healthy air.
Donate Now.


Breathe Easy

Give today and your tax-deductible gift will go TWICE as far for everyone who struggles to breathe.